4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]-
6-Nitro-4-[(3-chloro-4-fluorophenyl)amino]-7-[(R)-(tetrahydrofuran-3-yl)oxy]quinazoline
CAS: 402855-07-6
Molecular Formula: C18H14ClFN4O4
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]- - Names and Identifiers
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]- - Physico-chemical Properties
| Molecular Formula | C18H14ClFN4O4 |
| Molar Mass | 404.78 |
4-QuinazolinaMine, N-(3-chloro-4-fluorophenyl)-6-nitro-7-[[(3R)-tetrahydro-3-furanyl]oxy]- - Introduction
6-Nitro-4-[(3-chroo-4-fluorophenyl) amino]-7-[(R)-(tetrahydrofuran-3-yl)oxy]quinazoline is an organic compound commonly used in the field of medical research. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C19H15ClF2N4O4
-Molecular weight: 438.8g/mol
-Melting point: 220-225°C
-Soluble: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane
Use:
-Pharmaceutical Research: This compound is often used in the development of anti-cancer drugs because it inhibits the growth of tumor cells.
-Anti-tumor activity: This compound can interfere with the proliferation and DNA replication process of tumor cells by inhibiting tumor-related targets, such as tyrosine kinase (TK) and topoisomerase I (Topo I), thereby helping to treat certain types of cancer.
Preparation Method:
the preparation method of -6-Nitro-4-[(3-chloro-4-fluorophenyl)amino]-7-[(R)-(tetrahydrofuran-3-yl)oxy]quinazoline is relatively complicated, and generally needs to go through multiple steps of organic synthesis reaction to synthesize.
-Among them, tetrahydrofuran and 3-chloro-4-fluorophenylamine are the key intermediates for the preparation of this compound.
Safety Information:
-Because this is an organic compound, there is a certain potential danger.
-Avoid inhalation, ingestion or contact with skin and eyes. Wear appropriate protective equipment, including gloves and goggles, during use or handling.
-When performing laboratory operations with this compound, work in a well-ventilated place.
-When handling this compound, it is important to follow relevant laboratory safety procedures and guidelines to ensure safety and compliance.
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C19H15ClF2N4O4
-Molecular weight: 438.8g/mol
-Melting point: 220-225°C
-Soluble: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane
Use:
-Pharmaceutical Research: This compound is often used in the development of anti-cancer drugs because it inhibits the growth of tumor cells.
-Anti-tumor activity: This compound can interfere with the proliferation and DNA replication process of tumor cells by inhibiting tumor-related targets, such as tyrosine kinase (TK) and topoisomerase I (Topo I), thereby helping to treat certain types of cancer.
Preparation Method:
the preparation method of -6-Nitro-4-[(3-chloro-4-fluorophenyl)amino]-7-[(R)-(tetrahydrofuran-3-yl)oxy]quinazoline is relatively complicated, and generally needs to go through multiple steps of organic synthesis reaction to synthesize.
-Among them, tetrahydrofuran and 3-chloro-4-fluorophenylamine are the key intermediates for the preparation of this compound.
Safety Information:
-Because this is an organic compound, there is a certain potential danger.
-Avoid inhalation, ingestion or contact with skin and eyes. Wear appropriate protective equipment, including gloves and goggles, during use or handling.
-When performing laboratory operations with this compound, work in a well-ventilated place.
-When handling this compound, it is important to follow relevant laboratory safety procedures and guidelines to ensure safety and compliance.
Last Update：2024-04-09 21:04:16
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